18F-AlF-PSMA-11

18F-AlF-PSMA-11

Clinical area: Oncology Indication(s): Prostate cancer Clinical stage: Phase II Mechanism of action: PSMA Drug type: D Year of discovery – IP: 2018– IP4 Est. year of launch: 2027 Market size: 3 Freedom to operate: 1 Level of financing: 1 Development stage: 2 Description¹⁸F-AlF-PSMA-11 (also referred to as ¹⁸F-AlF-PSMA-HBED-CC or… Continue Reading…

18F-AlF-NOTA-Octreotide

18F-AlF-NOTA-Octreotide

Clinical area: Oncology Indication(s): NET Clinical stage: Phase II/III Mechanism of action: SSTR Drug type: D Year of discovery – IP: <2010 – IP2 Est. year of launch: >2025 Market size: 3 Freedom to operate: 1 Level of financing: 2 Development stage: 3 Description18F-AlF-NOTA-octreotide (also known as 18F-AlF-1,4,7-triazacyclononane-1,4,7-triacetate-octreotide, 18F-IMP466, and… Continue Reading…

18F-Alfatide and 18F-Alfatide II

18F-Alfatide and 18F-Alfatide II

Clinical area: Oncology Indication(s): Angiogenesis Clinical stage: Phase I/II Mechanism of action: RGD Drug type: D Year of discovery – IP: <2013 – IP3 Est. year of launch: >2025 Market size: 3 Freedom to operate: 2 Level of financing: 1 Development stage: 2 Description ¹⁸F-Alfatide (also known as ¹⁸F-AlF-NOTA-PRGD2 or… Continue Reading…

201Tl-Thallium Chloride

201Tl-Thallium Chloride

Description 201Tl-Thallium Chloride, also known as 201Tl-Thallous Chloride, is a widely used radioactive salt. It plays a critical role in myocardial perfusion imaging (MPI), a diagnostic imaging technique that evaluates blood flow to the heart muscle. Clinical Applications 1. Myocardial Perfusion Imaging (MPI):201Tl-Thallium Chloride is a valuable tool for diagnosing… Continue Reading…

133Xe-Xenon (Gas)

133Xe-Xenon (Gas)

Description133Xe-Xenon serves as a diagnostic radiopharmaceutical. It is primarily used as a gas (5% diluted in carbon dioxide) for evaluating pulmonary function and lung imaging. Additionally, a saline solution form allows its use in cerebral blood flow assessment. Clinical ApplicationsThe gas form of 133Xe-Xenon helps in lung ventilation imaging. Typical… Continue Reading…

131I-Sodium Iodide (131I-NaI)

131I-Sodium Iodide (131I-NaI)

Description 131I-Sodium Iodide (131I-NaI) is a cornerstone diagnostic and therapeutic radiopharmaceutical widely used for thyroid-related diseases, including thyroid carcinomas. It is typically administered as swallowable gelatin capsules, although liquid and injectable forms are also available. Introduced as the first radiotherapeutic in humans in 1941, it became a standard treatment by… Continue Reading…

131I-Iodohippurate (OIH)

131I-Iodohippurate (OIH)

Description 131I-Iodohippurate (also known as 131I-orthoiodohippurate or 131I-OIH) is a radiopharmaceutical agent designed for kidney imaging and function evaluation. It is specifically utilized for assessing tubular secretion, a critical parameter in renal function studies. This tracer has been a valuable tool in nuclear medicine for decades, helping clinicians gain insights… Continue Reading…

131I-Iobenguane (MIBG)

131I-Iobenguane (MIBG)

Description 131I-Iobenguane (commonly referred to as 131I-Metaiodobenzylguanidine or 131I-MIBG) is a radiopharmaceutical used both diagnostically and therapeutically for primary and metastatic pheochromocytomas and paragangliomas. This compound specifically targets adrenergic tissues, making it effective in localizing these neuroendocrine tumors. Azedra™ (formerly known as MIP-120T or Ultratrace MIBG), developed by Progenics (previously… Continue Reading…

131I-Human Serum Albumin

131I-Human Serum Albumin

Description 131I-Human Serum Albumin (131I-HSA) is a radiopharmaceutical agent utilized in medical diagnostics, primarily for human fluid analysis and imaging applications. It plays a crucial role in determining total blood and plasma volumes for blood analysis and is also employed in the localization of cerebral neoplasms during imaging procedures. Clinical… Continue Reading…

131I-Adosterol (Norcholesterol)

131I-Adosterol (Norcholesterol)

Overview 131I-Adosterol, also known as 131I-6-iodomethylnorcholesterol, 6-β-iodomethyl-19-nor-cholest-5(10)-en-3-β-ol, 131I-NP-59, or NCL-6-131I, is a radiolabeled cholesterol derivative commonly used in the diagnosis and investigation of adrenocortical disorders. Occasionally, it is mistakenly referred to as 131I-Aldosterol. This specialized compound plays a vital role in medical imaging, particularly in adrenal gland assessments. Clinical Applications… Continue Reading…

127Xe-Xenon (Gas)

127Xe-Xenon (Gas)

Description: Xenon-127 is a radioactive gas historically used for pulmonary imaging. It was initially available in the U.S. through Mallinckrodt but was withdrawn from the market in the mid-1980s. However, it is still produced by the Oak Ridge National Laboratory (ORNL) for research purposes. It is important to note that… Continue Reading…

125I-Human Serum Albumin (HSA)

125I-Human Serum Albumin (HSA)

Description:Iodinated Human Serum Albumin labeled with iodine-125 (125I-HSA) is a specialized radiopharmaceutical used for measuring plasma volume (PV) and total blood volume (TBV). Its unique properties make it indispensable for certain clinical and research applications. Clinical Applications 125I-HSA is a powerful tool in biological analysis, particularly for determining plasma volume… Continue Reading…